Glioblastoma Multiforme: Relationship to Subventricular Zone and Recurrence

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منابع مشابه

Relationship of glioblastoma multiforme to the subventricular zone is associated with survival.

The subventricular zone (SVZ) lines the lateral ventricles and represents the origin of neural and some cancer stem cells. Tumors contacting the SVZ may be more invasive with higher potential to recruit migratory progenitor cells. Our specific aim was to determine whether SVZ involvement in glioblastoma multiforme (GBM) is associated with a higher recurrence rate and shorter overall survival. M...

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Glioblastoma Multiforme and Adult Neurogenesis in the Ventricular-Subventricular Zone: A Review.

Brain cancers account for <1,5% of all new cancer cases reported in the United States each year. Due to their invasive and heterogeneous nature, in addition to their resistance to multimodal treatments, these tumors are usually fatal. Gliomas, and in particular high-grade astrocytomas such as glioblastoma multiforme (GBM), are the most common and lethal primary tumors of the central nervous sys...

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Glioblastoma recurrence patterns after radiation therapy with regard to the subventricular zone.

PURPOSE We evaluated the influence of tumor location and tumor spread in primary glioblastoma (GBM), with respect to the subventricular zone (SVZ), on recurrence behavior, progression-free survival (PFS), and overall survival (OS). METHODS AND MATERIALS 607 patients (376 male and 231 female) with a median age of 61.3 years (range, 3.0-87.9 years) and primary GBM treated with radiation therapy...

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Lateral ventricule invasion and radiation dose to subventricular zone: Their impact to the treatment outcomes of glioblastoma

Background: This study was conducted to evaluate the recurrence patterns of GBM in regard to its contact with LVs, the relation between radiation doses to subventrivular zone (SVZ). Materials and Methods: Between 2012 and 2014, 80 adult patients with GBM were included this trial. Median follow-up period was 15 months. Median tumor size was 4.5 cm (1.3-8 cm), where 58% of the patients had a tumo...

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Incidentalomas to glioblastoma multiforme

In April 1999, a 25-year-old male underwent magnetic resonance imaging (MRI) as a control subject for a multiple sclerosis study. The scan serendipitously revealed two lesions ('incidentalomas') in the right frontal lobe. Initially, he was asymptomatic and was monitored with interval MRI scans. After years of monitoring, contact was accidentally lost. He later presented following a witnessed ge...

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ژورنال

عنوان ژورنال: The Neuroradiology Journal

سال: 2013

ISSN: 1971-4009,2385-1996

DOI: 10.1177/197140091302600507